Anti-Angiogenic RNAi-Based Treatment of Endometriosis in a Rat Model Using CXCR4-Targeted Peptide Nanoparticles

Anti-Angiogenic RNAi-Based Treatment of Endometriosis in a Rat Model Using CXCR4-Targeted Peptide Nanoparticles Full article

Journal

International Journal of Molecular Sciences
ISSN: 1661-6596 , E-ISSN: 1422-0067

Output data

Year: 2025, Volume: 26, Article number : 10582, Pages count : DOI: 10.3390/ ijms262110582

Tags

endometriosis; anti-angiogenic therapy; siRNA delivery; peptide-based carriers; gene therapy; VEGFA; CXCR4; chemokine-derived peptide

Authors

Egorova A. ¹ , Freund S. ¹ , Krylova I. ² , Kislova A. ¹ , Kiselev A. ¹

Affiliations

1	Laboratory of Molecular Genetics and Gene Therapy, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology
2	Department of Pathology, Pavlov First Saint-Petersburg State Medical University

Funding (1)

РНФ

24-15-00498

Egorova A. , Freund S. , Krylova I. , Kislova A. , Kiselev A.
Anti-Angiogenic RNAi-Based Treatment of Endometriosis in a Rat Model Using CXCR4-Targeted Peptide Nanoparticles
International Journal of Molecular Sciences. 2025. Т.26. 10582 . DOI: 10.3390/ ijms262110582

Submitted:	Oct 1, 2025
Accepted:	Oct 29, 2025
Published online:	Oct 30, 2025

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