A profile of the FDA-approved and CE/IVD-marked AptimaMycoplasma genitaliumassay (Hologic) and key priorities in the management ofM. genitaliuminfections Научная публикация
| Журнал |
Expert Review of Molecular Diagnostics
ISSN: 1473-7159 , E-ISSN: 1744-8352 |
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| Вых. Данные | Год: 2020, Том: 20, Номер: 11, Страницы: 1063-1074 Страниц : 12 DOI: 10.1080/14737159.2020.1842198 | ||||
| Ключевые слова | Cervicitis; molecular diagnostics; nucleic acid amplification test (NAAT); sexually transmitted infection; transcription-mediated amplification; urethritis | ||||
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Реферат:
Introduction: Mycoplasma genitalium (MG) causes frequently asymptomatic STIs. MG prevalence figures are lacking and management is complicated by the lack of etiological diagnostics and high antimicrobial resistance in many countries. Appropriately validated, quality-assured, and FDA-approved MG diagnostic assays have been lacking.
Areas covered: The clinical and analytical performance characteristics of the Aptima® MG assay, the first FDA-approved MG nucleic acid amplification test (NAAT), are summarized. Key priorities in the management and control of MG infections are also discussed.
Expert opinion: Highly sensitive, specific, and quality-assured MG NAATs, e.g. the Aptima MG assay on the automated and flexible Panther® platform, are imperative to improve the management and control of MG infections internationally. This testing, combined with macrolide-resistance testing (not yet available on the Panther platform), offers a rapid, high-throughput, and appropriate diagnosis of MG. Macrolide resistance-guided sequential treatment needs to be implemented for MG infections. Dual antimicrobial therapy, novel antimicrobials and, ideally, a vaccine may become essentia
Библиографическая ссылка:
Shipitsyna E.
, Unemo M.
A profile of the FDA-approved and CE/IVD-marked AptimaMycoplasma genitaliumassay (Hologic) and key priorities in the management ofM. genitaliuminfections
Expert Review of Molecular Diagnostics. 2020. V.20. N11. P.1063-1074. DOI: 10.1080/14737159.2020.1842198 WOS Scopus РИНЦ OpenAlex
A profile of the FDA-approved and CE/IVD-marked AptimaMycoplasma genitaliumassay (Hologic) and key priorities in the management ofM. genitaliuminfections
Expert Review of Molecular Diagnostics. 2020. V.20. N11. P.1063-1074. DOI: 10.1080/14737159.2020.1842198 WOS Scopus РИНЦ OpenAlex
Даты:
| Опубликована online: | 16 июн. 2022 г. |
Идентификаторы БД:
| Web of science: | WOS:000583431700001 |
| Scopus: | eid_2-s2.0-85094908935 |
| РИНЦ: | 45179364 |
| OpenAlex: | W3094105307 |