Реферат: In this review, an attempt was made to substantiate the possibility for neurotrophins to be involved in the development of immune tolerance based on data accumulated on neurotrophin content and receptor expression in the trophoblast and immune cells, in particular, in natural killer cells. Numerous research results are reviewed to show that the expression and localization of neurotrophins along with their high-affinity tyrosine kinase receptors and low-affinity p75NTR receptor in the mother-placenta-fetus system indicate the important role of neurotrophins as binding molecules in regulating the crosstalk between the nervous, endocrine, and immune systems in pregnancy. An imbalance between these systems can occur with tumor growth and pathological processes observed in pregnancy complications and fetal development anomalies.

Библиографическая ссылка: Milyutina Y.P. , Arutjunyan A.V. , Korenevsky A.V. , Selkov S.A. , Kogan I.Y.
Neurotrophins: are they involved in immune tolerance in pregnancy?
American Journal of Reproductive Immunology. 2023. V.89. N4. DOI: 10.1111/aji.13694 WOS Scopus РИНЦ OpenAlex

Даты:

Опубликована online:

15 февр. 2023 г.

Идентификаторы БД:

Web of science:	WOS:000936192400001
Scopus:	2-s2.0-85148647751
РИНЦ:	50309771
OpenAlex:	W4321003514

Цитирование в БД:

БД	Цитирований
OpenAlex	2
Web of science	1
Scopus	1

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